Researchers at St Vincent’s Hospital in Sydney have achieved a breakthrough in our understanding of dementia and a new way forward in its treatment. Through their discovery, the team restored nerve cell connections (synapses) in the brain that are destroyed by Alzheimer’s and which are thought to store memory.
St Vincent’s Sydney’s Professor Bryce Vissel said:
"RNA editing can be used as a 'molecular switch'. By flicking the switch in the mice models we use in our research we were able to stop the brain cell connections from breaking down.
“Remarkably, we discovered that by doing so we restored lost memory in the mice".