Researchers based at the Cleveland Clinic Lerner Research Institute found that by gradually reducing an enzyme in the brain called BACE1, they reversed the formation of amyloid plaques in the brains of mice with Alzheimer’s disease, improving their cognitive function. The scientists hope that this research will eventually produce drugs aimed at this enzyme in human brains. This discovery edges science closer to both a vaccine and a treatment for Alzheimer's Disease which, in an ageing population, is sorely needed.