The vaccine could work by creating an anti-saliva immune response in humans that prevents infection. In addition, after the mosquito bites a vaccinated human host, antibodies from the human attack the gut and salivary glands of the mosquito which reduces the survival of the mosquito. If successful in its imminent Zika clinical study, Imutex will further develop the technology in other mosquito-borne illnesses, including malaria, dengue and West Nile.
http://imutex.com/index.php/zika-vaccine-programme/
Jonathan Chrimes