Recent studies have been exploring a growing trend in combining immune checkpoint inhibitors with small-molecule inhibitors targeting different pathways. Currently, inhibitors are directed at molecules like EGFR, VEGFR, PI3K, MAPK pathway, STING, TLR, and ALK. This approach has shown promising tumor responses in selected patients. Learn more: https://immune-checkpoint.creative-biolabs.com/immune-checkpoint-therapy.htm
In the nervous system, efficient transmission of information along axons, in the form of electrical pulses over long distances, relies on myelin. Myelin, a lipid-rich specialized membrane, is produced by glial cells. In the central nervous system (CNS), oligodendrocytes, a type of glial cell, generate myelin. Learn more about Oligodendrocyte Differentiation: https://neurost.creative-biolabs.com/oligodendrocytes-differentiation-service.htm
Macrophages are a diverse cell group that can adapt to various conditions. Their identity and function can be shaped by the local tissue, activation signals, and origin. Studies have highlighted differences between human and mouse macrophages. Understanding human macrophages can aid in identifying them in diseases and developing new therapies. Learn more about Human Macrophage Characterization: https://macrophage.creative-biolabs.com/macrophage-characterization-service.htm
Mesenchymal stem cells (MSCs) are versatile cells with the potential for tissue regeneration and cell-based therapy because of their ability to become different cell types. To use MSCs effectively, they need to be isolated and guided to differentiate into specific lineages. Learn more about Mesenchymal Stem Cells Differentiation: https://www.creative-biolabs.com/stem-cell-therapy/mesenchymal-stem-cells-mscs-differentiation-services.htm
The FDA approval of two CAR-T cell therapies has increased the popularity of chimeric antigen receptor (CAR)-engineered T cell therapy in academic and clinical settings. Creative Biolabs has developed a comprehensive platform for CAR-T cell-based drug discovery, providing GMP-level services for plasmid preparation, virus packaging, and T cell production to support the discovery of new therapies. Learn more about CAR-T cell therapy manufacturing: https://www.creative-biolabs.com/car-t/gmp-production-for-car-t-products.htm
Creative Biolabs specializes in neuroscience research and is a top service provider. With our advanced platforms and extensive experience, we are confident in providing primary neuronal cell culture models for customers worldwide. Learn more: https://neuros.creative-biolabs.com/primary-neuronal-cell-culture-models.htm
